All in Tolerating Sin

Do we tolerate sin, even those that we feel are insignificant, and allow them to remain in us? When we let the smallest of sins hover over us, or make its home within us without addressing it, and casting it out, what effect does it have on us as a whole? When we allow it to go without feeling remorseful, contrite, and asking for forgiveness, then we suffer physically, mentally, emotionally, and most of all spiritually.